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Wound Healing

General Surgery • NEET MDS Study Guide • AI-Generated Notes

⭐ High-Yield Facts for Exam

  • Primary = clean sutured wound.
  • Secondary = granulation/contraction.
  • Tertiary = delayed primary closure.
  • Phases: hemostasis→inflammation→proliferation→remodeling.
  • Type III collagen → type I on remodeling.

Wound Healing

Types of Closure

  • Primary intention — clean, approximated edges (sutured); minimal scar.
  • Secondary intention — open wound heals by granulation, contraction and epithelialisation.
  • Tertiary (delayed primary) — wound left open then closed later (e.g., after infection control).

Phases

Hemostasis → Inflammation → Proliferation (granulation) → Remodeling (maturation). Early granulation tissue lays down type III collagen, later replaced by stronger type I collagen.

Factors

Healing is impaired by infection, diabetes, smoking, poor nutrition (vitamin C), ischaemia and steroids.

Exam Tips ⭐

Primary = sutured clean wound; phases hemostasis→inflammation→proliferation→remodeling; type III → type I collagen.

📝 Practice MCQs — Wound Healing

Q1. A clean, sutured wound heals by:
A. Secondary intention
B. Primary intention
C. Tertiary intention
D. No healing
Show Answer
✅ Answer: B
Approximated clean wounds heal by primary intention.
Q2. During remodeling, collagen changes from:
A. Type I to type III
B. Type III to type I
C. Type II to type IV
D. No change
Show Answer
✅ Answer: B
Early type III collagen is replaced by stronger type I.
Q3. The correct order of healing phases is:
A. Inflammation → Hemostasis → Remodeling
B. Hemostasis → Inflammation → Proliferation → Remodeling
C. Proliferation → Hemostasis → Inflammation
D. Remodeling → Proliferation → Inflammation
Show Answer
✅ Answer: B
Hemostasis, inflammation, proliferation, then remodeling.
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Related Topics

Sutures & Surgical InstrumentsSkin Grafts & FlapsSurgical Management of Cysts