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Lichen Planus & Lupus

Oral Medicine & Radiology • NEET MDS Study Guide • AI-Generated Notes

⭐ High-Yield Facts for Exam

  • Wickham striae = lichen planus.
  • Reticular = most common OLP; erosive = most symptomatic.
  • OLP histology = saw-tooth rete + band-like infiltrate.
  • Lupus = butterfly rash + lupus band test.
  • Anti-dsDNA = specific for SLE.

Lichen Planus & Lupus

Oral Lichen Planus (OLP)

  • Wickham's striae — fine white lacy lines, the hallmark of the reticular form (most common, usually asymptomatic).
  • Erosive form — most symptomatic; potentially malignant (low risk).
  • Histology: hyperkeratosis, saw-tooth rete ridges, basal cell degeneration, band-like T-lymphocyte infiltrate. DIF: shaggy fibrinogen at the BMZ.

Lupus Erythematosus

Butterfly (malar) rash in SLE; oral lesions may mimic lichen planus. The lupus band test shows a granular band of immunoglobulin at the BMZ; anti-dsDNA is specific for SLE.

Exam Tips ⭐

Wickham striae = lichen planus; reticular = most common; erosive = most symptomatic; butterfly rash + lupus band test = lupus.

📝 Practice MCQs — Lichen Planus & Lupus

Q1. Wickham's striae are seen in:
A. Lupus
B. Lichen planus
C. Pemphigus
D. Candidiasis
Show Answer
✅ Answer: B
Wickham's striae are the lacy hallmark of lichen planus.
Q2. The most common form of oral lichen planus is:
A. Erosive
B. Reticular
C. Bullous
D. Atrophic
Show Answer
✅ Answer: B
The reticular form is most common (Wickham's striae).
Q3. A specific antibody for SLE is:
A. Anti-dsDNA
B. Rheumatoid factor
C. Anti-CCP
D. ANCA
Show Answer
✅ Answer: A
Anti-dsDNA is specific for systemic lupus erythematosus.
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