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Biopsy Techniques

Oral & Maxillofacial Surgery • NEET MDS Study Guide • AI-Generated Notes

⭐ High-Yield Facts for Exam

  • Incisional = large/suspicious lesions, includes normal margin.
  • Excisional = small (<1 cm) lesions.
  • FNAC = deep masses/salivary/lymph nodes.
  • Brush biopsy = screening only.
  • Fix specimen in 10% formalin.

Biopsy Techniques

  • Incisional biopsy — removes a representative portion (with a margin of normal tissue) of a large or suspicious lesion for diagnosis before definitive treatment.
  • Excisional biopsy — removes the entire lesion; suited to small (<1 cm), benign-appearing lesions (both diagnostic and therapeutic).
  • FNAC (fine-needle aspiration cytology) — for deep masses, salivary glands and lymph nodes.
  • Brush biopsy — a screening/cytology tool for suspicious mucosal lesions (positive result needs scalpel confirmation).

Principles

Take representative tissue, avoid necrotic centres, orient and fix the specimen properly (10% formalin), and include a margin where indicated.

Exam Tips ⭐

Incisional = large lesions; excisional = small (<1 cm); FNAC = deep/lymph node/salivary; brush = screening.

📝 Practice MCQs — Biopsy Techniques

Q1. Which biopsy is best for a small (<1 cm) benign-looking lesion?
A. Incisional
B. Excisional
C. FNAC
D. Brush
Show Answer
✅ Answer: B
Excisional biopsy removes small lesions entirely.
Q2. FNAC is most useful for:
A. Surface ulcers
B. Deep masses, salivary glands, lymph nodes
C. Enamel defects
D. Caries
Show Answer
✅ Answer: B
FNAC samples deep masses, salivary glands and nodes.
Q3. A positive brush biopsy should be followed by:
A. No further action
B. Scalpel (tissue) biopsy confirmation
C. Extraction
D. Antibiotics
Show Answer
✅ Answer: B
Brush biopsy is a screening tool; positives need histologic confirmation.
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